Czech J. Food Sci., 2021, 39(5):340-359 | DOI: 10.17221/221/2020-CJFS

Methods for suppressing Fusarium infection during malting and their effect on malt qualityReview

Carlo Antonio Ng*,1, Michaela Po¹tulková1, Dagmar Matoulková2, Vratislav Psota2, Ivo Hartman2, Tomas Branyik1,2
1 Department of Biotechnology, Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Prague, Czech Republic
2 Research Institute of Brewing and Malting, Prague, Czech Republic

The incidence of Fusarium head blight (FHB) in cereal grains such as barley and wheat is of growing concern due to climate change threatening food safety. Further processing of cereals by malting provides an ideal environment for the growth of Fusarium, leading to food safety concerns due to the production of mycotoxins, production challenges with the negative effects to malt and beer qualities, and economic loss owing to the field yield reduction. To improve food safety and product quality, different methods of fungal control have been investigated and reported in the literature. Traditional methods to control fungal growth and mycotoxin production have included chemical and physical methods, but these treatments led to worsened malt properties, limiting their applicability to the brewing industry. Biological control methods have, therefore, attracted wide interest as alternative treatments due to their ability to limit Fusarium growth and mycotoxin production in malting cereals without toxic by-products, thus exhibiting promise for improving food safety. Various biological agents have been investigated and applied in malting and have shown the potential to suppress Fusarium spp. growth and mycotoxin production. These agents include several lactic acid bacterial (LAB) species and Geotrichum candidum. Another promising biocontrol agent for malting control is Pythium oligandrum, which has successfully limited Fusarium infection in other agricultural crops. The review outlines the Fusarium-control methods reported referenced for the brewing industry and the present prospects in biological control applications on the promise of P. oligandrum as a novel agent for malting.

Keywords: mycotoxins; malting; biological control; Pythium oligandrum

Published: October 14, 2021  Show citation

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Ng CA, Po¹tulková M, Matoulková D, Psota V, Hartman I, Branyik T. Methods for suppressing Fusarium infection during malting and their effect on malt quality. Czech J. Food Sci. 2021;39(5):340-359. doi: 10.17221/221/2020-CJFS.
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References

  1. Agriopoulou S., Stamatelopoulou E., Varzakas T. (2020): Advances in occurrence, importance, and mycotoxin control strategies: Prevention and detoxification in foods. Foods, 9: 137. Go to original source... Go to PubMed...
  2. Allen B., Wu J., Doan H. (2003): Inactivation of fungi associated with barley grain by gaseous ozone. Journal of Environmental Science and Health, Part B, 38: 617-630. Go to original source... Go to PubMed...
  3. Al-Rawahi A.K., Hancock J.G. (1998): Parasitism and biological control of Verticillium dahlia by Pythium oligandrum. Plant Diseases, 82: 1100-1106. Go to original source... Go to PubMed...
  4. Anderson H.E., Santos I.C., Hildenbrand Z.L., Schug K.A. (2019): A review of the analytical methods used for beer ingredients and finished product analysis and quality control. Analytical Chimica Acta, 1085: 1-20. Go to original source... Go to PubMed...
  5. Ayed F., Daami-Remadi M., Jabnoun-Khiareddine H., El Mahjoub M. (2007): In vitro and in vivo evaluation of some biofungicides for potato Fusarium wilt biocontrol. International Journal of Agricultural Research, 2: 282-288. Go to original source...
  6. Bartkiene E., Bartkevics V., Lele V., Pugajeva I., Zavistanaviciute P., Mickiene R., Zadeike D., Juodeikiene G. (2018): A concept of mould spoilage prevention and acrylamide reduction in wheat bread: Application of lactobacilli in combination with a cranberry coating. Food Control, 91: 284-293. Go to original source...
  7. Beccari G., Prodi A., Tini F., Bonciarelli U., Onofri A., Oueslati S., Limayma M., Covarelli L. (2017): Changes in the Fusarium head blight complex of malting barley in a three-year field experiment in Italy. Toxins, 9: 120. Go to original source... Go to PubMed...
  8. Benhamou N., Belanger R.R., Rey P., Tirilly Y. (2001): Oligandrin, the elicitin-like protein produced by Pythium oligandrum, induces systemic resistance to Fusarium crown and root rot in tomato plants. Plant Physiology and Biochemistry, 39: 681-698. Go to original source...
  9. Benhamou N., Rey P., Picard K., Tirilly Y. (1999): Ultrastructure and cytochemical aspects of the interaction between the mycoparasite Pythium oligandrum and soilborne plant pathogens. Phytopathology, 89: 506-517. Go to original source... Go to PubMed...
  10. Berthiller F., Crews C., Dall'A sta C., De Daeger S., Haesaert G., Karlovsky P., Oswald I.P., Seefelder W., Speijers G., Stroka J. (2013). Masked mycotoxins: A review. Molecular Nutrition & Food Research, 57: 165-186. Go to original source... Go to PubMed...
  11. Boivin P., Malanda M. (1999): United States of America Patent No. 5 955 070.
  12. Boeira L., Bryce J., Stewart G., Flannigan B. (2002): Influence of cultural conditions on sensitivity of brewing yeasts growth to Fusarium mycotoxins zearalenone, deoxynivalenol and fumonisin B1. International Biodeterioration & Biodegradation, 50: 69-81. Go to original source...
  13. Boutroua R., Guéguen M. (2005): Interests in Geotrichum candidum for cheese technology. International Journal of Food Microbiology, 102: 1-20. Go to original source... Go to PubMed...
  14. Calado T., Venâncio A., Abrunhosa L. (2014): Irradiation for mold and mycotoxin control: A review. Comprehensive Reviews in Food Science and Food Safety, 13: 1049-1061. Go to original source...
  15. Contreras-Jiménez B., Del Real A., Millan-Malo B.M., Gaytán-Martínez M., Morales-Sánchez E., Rodríguez-García M.E. (2017): Physiochemical changes in barley starch during malting. Journal of the Institute of Brewing, 125: 10-17. Go to original source...
  16. Corsetti A., Gobbetti M., Rossi J., Damiani P. (1998): Antimould activity of sourdough lactic acid bacteria: Identification of a mixture of organic acids produced by Lactobacillus sanfrancisco CB1. Applied Microbiology and Biotechnology, 50: 253-256. Go to original source... Go to PubMed...
  17. Dalié D.K.D., Deschamps A.M., Richard-Forget F. (2010): Lactic acid bacteria - Potential for control of mould growth and mycotoxins: A review. Food Control, 21: 370-380. Go to original source...
  18. Dodd J.G., Vegi A., Vashisht A., Tobias D., Schwarz P., Wolf-Hall C.E. (2011): Effect of ozone treatment on the safety and quality of malting barley. Journal of Food Protection, 74: 2134-2141. Go to original source... Go to PubMed...
  19. European Commission (2017): Risk to human and animal health related to the presence of deoxynivalenol and its acetylated and modified forms in food and feed. EFSA Journal, 15: 4718.
  20. Evans D.E., Redd K., Haraysmow S.E., Elvig N., Metz N., Koutoulis A. (2014): The influence of malt quality on malt brewing and barley quality on barley brewing with Ondea Pro, compared by small-scale analysis. Journal of the American Society of Brewing Chemists, 72: 192-207. Go to original source...
  21. Feizollahi E., Roopesh M.S. (2021): Mechanisms of deoxynivalenol (DON) degradation during different treatments: A review. Critical Reviews in Food Science and Nutrition, 64: 1-24.
  22. Freire L., Sant'Ana A.S. (2018): Modified mycotoxins: An updated review on their formation, detection, occurrence, and toxic effects. Food and Chemical Toxicology, 111: 189-205. Go to original source... Go to PubMed...
  23. Foszczyñska B., Dziuba E., Stempniewicz R. (2004): The use of Geotrichum candidum starter culture for protection of barley and its influence on biotechnological qualities of malt. Electronic Journal of Polish Agricultural Universities, 7: 04.
  24. Garmendia G., Pattarino L., Negrín C., Martínez-Silveira A., Pereyra S., Ward T., Vero S. (2018): Species composition, toxigenic potential and aggressiveness of Fusarium isolates causing head blight of barley in Uruguay. Food Microbiology, 76: 426-433. Go to original source... Go to PubMed...
  25. Geissinger C., Hofer K., Habler K., Hess M., Hückelhoven R., Rychlik M., Becker T., Gastl M. (2017): Fusarium species on barley malt: Is visual assessment an appropriate tool for detection? Cereal Chemistry, 94: 659-669. Go to original source...
  26. Habler K., Geissinger C., Hofer K., Schüler J., Moghari S., Hess M., Gastl M., Rychlik M. (2017): Fate of Fusarium toxins during brewing. Journal of Agricultural and Food Chemistry, 65: 190-198. Go to original source... Go to PubMed...
  27. Habler K., Moghari S., Rychlik M. (2018): Analysis of Fusarium toxins in single barley malt kernels. Journal of Analysis and Testing, 2: 124-137. Go to original source...
  28. Habschied K., Krska R., Sulyok M., ©arkanj B., Krstanoviæ V., Laliæ A., ©imiæ G., Mastanjeviæ K. (2019): Screening of various metabolites in six barley varieties grown under natural climatic conditions (2016-2018). Microorganisms, 7: 532. Go to original source... Go to PubMed...
  29. Hofer K., Geissinger C., König C., Gastl M., Hückelhoven R., Hess M., Coleman A.D. (2016): Influence of Fusarium isolates on the expression of barley genes related to plant defense and malting quality. Journal of Cereal Science, 69: 17-24. Go to original source...
  30. Hofer K., Hückelhoven R., Hess M. (2019): Analysis of archive samples of spring and winter barley support an increase in individual Fusarium species in Bavarian barley grain over the last decades. Journal of Plant Diseases and Protection, 126: 247-254. Go to original source...
  31. Horackova S., Novakova T., Slukova M., Bialasova K., Kumherova M., Plockova M. (2018): Antifungal activity of selected lactobacilli intended for sourdough production. Applied Food Biotechnology, 5: 213-220.
  32. Hrubo¹ová D., Vytøasová J., Bro¾ková I. (2015): Production of T-2 toxin and deoxynivalenol in the presence of different disinfectants. Potravinarsto, 9: 18-23. Go to original source...
  33. Hückelhoven R., Hofer K., Coleman A., Hess M. (2018): Fusarium infection of malting barley has to be managed over the entire value chain. Journal of Plant Diseases and Protection, 125: 1-4. Go to original source...
  34. Ikeda S., Shimizu A., Shimizu M., Takahashi H., Takenaka S. (2012): Biocontrol of black scurf on potato by seed tuber treatment with Pythium oligandrum. Biological Control, 60: 297-304. Go to original source...
  35. Iwase C.H.T., Piacentini K.C., Giomo P.P., Èumová M., Wawroszová S., Bìláková S., Minella E., Rocha L.O. (2020): Characterization of the Fusarium sambucinum species complex and detection of multiple mycotoxins in Brazilian barley samples. Food Research International, 136: 109336. Go to original source... Go to PubMed...
  36. Janssen E., Liu C., Van der Fels-Klerx H. (2018): Fusarium infection and trichothecenes in barley and its comparison with wheat. World Mycotoxin Journal, 11: 33-46. Go to original source...
  37. Jestoi M.N., Paavanen-Huhtala S., Parikka P., Yli-Mattila T. (2008): In vitro and in vivo mycotoxin production of Fusarium species isolated from Finnish grains. Archives of Phytopathology and Plant Protection, 41: 545-558. Go to original source...
  38. Jin Z., Gillespie J., Barr J., Wiersma J.J., Sorrells M.E., Zwinger S., Gross T., Cumming J., Bergstrom G.C., Brueggeman R., Horsley R.D., Schwarz P.B. (2018): Malting of Fusarium head blight-infected rye (Secale cereale): Growth of Fusarium graminearum, trichothecene production, and the impact on malt quality. Toxins, 10: 369. Go to original source... Go to PubMed...
  39. Jukonyte R., Zadeike D., Bartkiene E., Lele V., Cernaukas D., Suproniene S., Juodeikiene G. (2018): A potential of brown rice polish as a substrate for the lactic acid and bioactive compounds production by lactic acid bacteria newly isolated from cereal-based fermented products. LWT - Food Science and Technology, 87: 323-331. Go to original source...
  40. Juodeikiene G., Bartkiene E., Cernauskas D., Cizeikiene D., Zadeike D., Lele V., Bartkevics V. (2018): Antifungal activity of lactic acid bacteria and their application for Fusarium mycotoxin reduction in malting wheat grains. LWT - Food Science and Technology, 89: 307-314. Go to original source...
  41. Khalesi M., Deckers S., Riveros-Galan D., Gebruers K., Derdelinckx G. (2015): Upgraded model of primary gushing: From nanobubble formation until liquid expulsion. Journal of the American Society of Brewing Chemists, 73: 343-346. Go to original source...
  42. Kharazian Z.A., Aghdasi M., Jouzan G.S., Zamani M. (2017): Effects of Fusarium verticilliodes and Lactobacillus strains inoculation of growth and antioxidant enzyme activity of Zea mays plants. Journal of Horticultural Research, 5: 67-74. Go to original source...
  43. Kottapalli B., Wolf-Hall C.E. (2008): Effect of hot water treatments on the safety and quality of Fusarium-infected malting barley. International Journal of Food Microbiology, 124: 171-178. Go to original source... Go to PubMed...
  44. Kottapalli B., Wolf-Hall C.E., Schwarz P. (2005): Evaluation of gaseous ozone and hydrogen peroxide treatments for reducing Fusarium survival in malting barley. Journal of Food Protection, 68: 1236-1240. Go to original source... Go to PubMed...
  45. Kottapalli B., Wolf-Hall C.E., Schwarz P. (2006): Effect of electron-beam irradiation on the safety and quality of Fusarium-infected malting barley. International Journal of Food Microbiology, 110: 224-231. Go to original source... Go to PubMed...
  46. Kottapalli B., Wolf-Hall C.E., Schwarz P., Schwarz J., Gillespie J. (2003): Evaluation of hot water and electron beam irradiation for reducing Fusarium infection in malting barley. Journal of Food Protection, 66: 1241-1246. Go to original source... Go to PubMed...
  47. Ksieniewicz-Wo¼niak E., Bry³a M., Wa¶kiewicz A., Yoshinari T., Szymczyk K. (2019): Selected trichothecenes in barley malt and beer from Poland and an assessment of dietary risks associated with their consumption. Toxins, 11: 715. Go to original source... Go to PubMed...
  48. Laitila A., Alakomi H.L., Mattila-Sandholm T., Haikara A. (2002): Antifungal activities of two Lactobacillus plantarum strains against Fusarium moulds in vitro and in malting barley. Journal of Applied Microbiology, 93: 566-576. Go to original source... Go to PubMed...
  49. Laitila A., Sarlin T., Kotaviita E., Huttunen T., Home S., Wilhelmson A. (2007): Yeast isolated from industrial maltings can suppress Fusarium growth and formation of gushing factors. Journal of Industrial Microbiology and Biotechnology, 34: 701-713. Go to original source... Go to PubMed...
  50. Laitila A., Sarlin T., Raulio M., Wilhelmson A., Kotaviita E., Huttunen T., Juvonen R. (2011): Yeast in malting, with special emphasis on Wicherhamomyces anomalus. Antonie van Leeuwenhoek, 99: 75-84. Go to original source... Go to PubMed...
  51. Laitila A., Sweins H., Vilpola A., Kotaviita E., Olkku J., Home S., Haikara A. (2006): Lactobacillus plantarum and Pediococcus pentosaceus starter cultures as a tool for microflora management in malting and enhancement of malt processability. Journal of Agricultural and Food Chemistry, 54: 3840-3851. Go to original source... Go to PubMed...
  52. Lake J., Browers M., Yin X.S., Speers R.A. (2007). Use of sodium bisulfite as a method to reduce DON levels in barley during malting. Journal of the American Society of Brewing Chemists, 65: 172-176. Go to original source...
  53. Lancova K., Hajslova J., Poustka J., Krplova A., Zachariasova M., Dostalek P., Sachambula L. (2008): Transfer of Fusarium mycotoxins and 'masked' deoxynivalenol (deoxynivalenol-3-glucoside) from field barley through malt to beer. Food Additives and Contaminants, 25: 732-744. Go to original source... Go to PubMed...
  54. Langseth W., Bernhoft A., Runberget T., Kosiak B., Gareis M. (1999): Mycotoxin production and cytotoxicity of Fusarium strains isolated from Norwegian cereals. Mycopathologia, 144: 103-113. Go to original source... Go to PubMed...
  55. Linkmeyer A., Hofer K., Rychlik M., Herz M., Hausladen H., Hückelhoven R., Hess M. (2016): Influence of inoculum and climatic factors on the severity of Fusarium head blight in German spring and winter barley. Food Additives and Contaminants: Part A, 33: 489-499. Go to original source... Go to PubMed...
  56. Liske R.B., Niessen L., Vogel R.F. (2000): Potential of lactic acid bacteria to reduce the growth of Fusarium culmorum in the malting process. Mycotoxin Research, 16: 62-65. Go to original source... Go to PubMed...
  57. Lowe D.P., Arendt E.K. (2004): The use and effects of lactic acid bacteria in malting and brewing with their relationship to antifungal activity, mycotoxins and gushing: A review. Journal of the Institute of Brewing, 110: 163-180. Go to original source...
  58. Lowe D.P., Arendt E.K., Soriano A.M., Ulmer H.M. (2005): The influence of lactic acid bacteria on the quality of malt. Journal of the Institute of Brewing, 111: 42-50. Go to original source...
  59. Lowe D.P., Ulmer H.M., Graser K., Arendt E.K. (2006): The influence of starter cultures on barley contaminated with Fusarium culmorum TMW 4.0754. Journal of the American Society of Brewing Chemists, 64: 157-165. Go to original source...
  60. Madgwick J.W., West J.S., White R.P., Semenov M.A., Townsend J.A., Turner J.A., Fitt B.D.L. (2011): Impacts of climate change on wheat anthesis and Fusarium war blight in the UK. European Journal of Plant Pathology, 130: 117-131. Go to original source...
  61. Malachova A., Cerkal R., Ehrenbergerova J., Dzuman Z., Vaculova K., Hajslova J. (2010): Fusarium mycotoxins in various barley cultivars and their transfer into malt. Journal of the Science of Food and Agriculture, 90: 2495-2505. Go to original source... Go to PubMed...
  62. Mallmann C., Dilkin P., Mallmann A., Oliveira M., Adaniya Z., Tonini C. (2017): Prevalence and levels of deoxynivalenol and zearalenone in commercial barley and wheat grain produced in Southern Brazil: An eight-year (2008 to 2015) summary. Tropical Plant Pathology, 42: 146-152. Go to original source...
  63. Marin S., Ramos A.J., Cano-Sancho G., Sanchis V. (2013): Mycotoxins: Occurrence, toxicology, and exposure assessment. Food and Chemical Toxicology, 60: 218-237. Go to original source... Go to PubMed...
  64. Mastanjeviæ K., Krstanoviæ V., Lukinac J., Mastanjeviæ K. (2018): Impact of Fusarium infection and fungicide treatment on wheat malt wort quality. Journal of the Institute of Brewing, 124: 204-208. Go to original source...
  65. Mauch A., Dal Bello F., Coffey Z., Arendt E.K. (2010): The use of Lactobacillus brevis PS1 to in vitro inhibit the outgrowth of Fusarium culmorum and other common Fusarium species found on barley. International Journal of Food Microbiology, 141: 116-121. Go to original source... Go to PubMed...
  66. McKee G., Cowger C., Dill-Macky R., Friskop A., Gautam P., Ransom J., Wilson W. (2019): Disease management and estimated effects on DON (deoxynivalenol) contamination in Fusarium infested barley. Agriculture, 9: 155. Go to original source...
  67. Moretti A., Pascale M., Logrieco A.F. (2019): Mycotoxin risks under a climate change scenario in Europe. Trends in Food Science & Technology, 84: 38-40. Go to original source...
  68. Munkvold G. (2017): Fusarium species and their associated mycotoxins. Methods in Molecular Biology, 1542: 51-106. Go to original source... Go to PubMed...
  69. Munkvold G.P., Arias S., Taschl I., Gruber-Dorninger C. (2019): Mycotoxins in corn: Occurrence, impacts, and management. In: Serna-Saldivar S.O. (ed.): Corn. 3rd Ed. Place of Publisher, Woodhead Publishing and AACC International Press: 235-287. Go to original source...
  70. Munkvold G.P., Proctor R.H., Moretti A. (2021): Mycotoxin production in Fusarium according to contemporary species concepts. Annual Review of Phytopathology, 59: 373-402. Go to original source... Go to PubMed...
  71. Nielsen L., Cook D., Edwards S., Ray R. (2014): The prevalence and impact of Fusarium head blight pathogens and mycotoxins on malting barley quality in UK. International Journal of Food Microbiology, 179: 38-49. Go to original source... Go to PubMed...
  72. Ng C.A., Pernica M., Yap J., Belakova S., Vaculova K., Branyik T. (2021): Biocontrol effect of Pythium oligandrum on artificial Fusarium culmorum infection during malting of wheat. Journal of Cereal Science, 100: 103258. Go to original source...
  73. Nogueira M., Decundo J., Martinez M., Dieguez S., Moreyra F., Moreno M., Stenglein S. (2018): Natural contamination with mycotoxins produced by Fusarium graminearum and Fusarium poae in malting barley in Argentina. Toxins, 10: 78. Go to original source... Go to PubMed...
  74. Oliveira P.M., Brosnan B., Furey A., Coffey A., Zannini E. (2015a): Lactic acid bacteria bioprotection applied to the malting process. Part I: Strain characterization and identification of antifungal compounds. Food Control, 51: 433-443. Go to original source...
  75. Oliveira P.M., Zannini E., Arendt E.K. (2014): Cereal fungal infection, mycotoxins, and lactic acid bacteria mediated bioprotection: From crop farming to cereal products. Food Microbiology, 37: 78-95. Go to original source... Go to PubMed...
  76. Oliveira P., Brosnan B., Jacob F., Furey A., Coffey A., Zannini E., Arendt E.K. (2015b): Lactic acid bacteria bioprotection applied to the malting process. Part II: Substrate impact and mycotoxin reduction. Food Control, 51: 444-452. Go to original source...
  77. Oliveira P., Mauch A., Jacob F., Arendt E.K. (2012): Impact of Fusarium culmorum-infected barley malt grains on brewing and beer quality. Journal of the American Society of Brewing Chemists, 70: 186-194. Go to original source...
  78. Parikka P., Hakala K., Tiilikkala K. (2012): Expected shifts in Fusarium species' composition on cereal grain in Northern Europe due to climatic change. Food Additives & Contaminants: Part A, 29: 1543-1555. Go to original source... Go to PubMed...
  79. Paris M.P.K., Schweiger W., Hametner C., Stückler R., Muehlbauer G.J., Varga E., Krska R., Berthiller F., Adam G. (2014): Zearalenone-16-O-glucoside: A new masked mycotoxin. Journal of Agriculture and Food Chemistry, 62: 1181-1189. Go to original source... Go to PubMed...
  80. Pascari X., Ramos A.J., Marín S., Sanchís V. (2018): Mycotoxins and beer. Impact of beer production process on mycotoxin contamination. A review. Food Research International, 103: 121-129. Go to original source... Go to PubMed...
  81. Perczak A., Goliñski P., Bry³a M., Wa¶kiewicz A. (2018): The efficiency of lactic acid bacteria against pathogenic fungi and mycotoxins. Arhiv za Higijenu Rada i Toksikologiju, 69: 32-45. Go to original source... Go to PubMed...
  82. Peyer L.C., Axel C., Lynch K.M., Zannini E., Jacob F., Arendt E.K. (2016): Inhibition of Fusarium culmorum by carboxylic acid release from lactic acid bacteria in a barley malt substrate. Food Control, 69: 227-236. Go to original source...
  83. Piacentini K., Bìláková S., Bene¹ova K., Pernica M., Savi G., Rocha L., Hartman I., Èáslavský J., Corrêa B. (2019a): Fusarium mycotoxins stability during the malting and brewing process. Toxins, 11: 257. Go to original source... Go to PubMed...
  84. Piacentini K., Rocha L., Savi G., Carnielli-Queiroz L., Fontes L., Correa B. (2019b): Assessment of toxigenic Fusarium species and their mycotoxins in brewing barley grains. Toxins, 11: 31. Go to original source... Go to PubMed...
  85. Piegza M., Witkowska D., Stempniewicz R. (2014): Enzymatic and molecular characteristics of Geotrichum candidum strains as starter culture for malting. Journal of the Institute of Brewing, 120: 341-346. Go to original source...
  86. Piegza M., Witkowska D., Stempniewicz R., Rywiñska A. (2005): Geotrichum candidum activity in milled malt and barley medium. Electronic Journal of Polish Agricultural Universities, 8: 15.
  87. Postulkova M., Rezanina J., Fiala J., Ruzicka M.C., Dostalek P., Branyik T. (2018): Suppression of fungal contamination by Pythium oligandrum during malting of barley. Journal of the Institute of Brewing, 124: 336-340. Go to original source...
  88. Postulkova M., Riveros-Galan D., Cordova-Aguilar K., Zitkova K., Verachtert H., Derdelinckx G., Dostalek P., Ruzicka M.C., Branyik T. (2016): Technological possibilities to prevent and suppress primary gushing of beer. Trends in Food Science & Technology, 49: 64-73. Go to original source...
  89. Ramakrishna N., Lacey J., Smith J.E. (1991): Effect of surface sterilization, fumigation and gamma irradiation on the microflora and germination of barley seeds. International Journal of Food Microbiology, 13: 47-54. Go to original source... Go to PubMed...
  90. Poli¹enská A., Vaculová K., Jirsa O., Sedláèhová I., Frydrych J. (2019): Yield and quality of two hulless barley varieties after inoculation with Fusarium culmorum. Kvasný Prùmysl, 65: 17-22. Go to original source...
  91. Psota V., Kosaø K. (2002): Malting quality index. Kvasný Prùmysl, 48: 142-148. Go to original source...
  92. Psota V., Musilová M. (2020): System for the evaluation of malting quality of wheat varieties. Kvasný Prùmysl, 66: 232-238. Go to original source...
  93. Rood L., Koutoulis A., Bowman J.P., Evans D.E., Stanley R.A., Kaur M. (2018): Control of microbes on barley grains using peracetic acid and electrolyzed water as antimicrobial agents. Food Microbiology, 76: 103-109. Go to original source... Go to PubMed...
  94. Rouse S., van Sinderen D. (2008): Bioprotective potential of lactic acid bacteria in malting and brewing. Journal of Food Protection, 71: 1724-1733. Go to original source... Go to PubMed...
  95. Russo P., Arena M.P., Fiocco D., Capozzi V., Drider D., Spano G. (2017): Lactobacillus plantarum with broad antifungal activity: A promising approach to increase safety and shelf-life of cereal-based products. International Journal of Food Microbiology, 247: 48-54. Go to original source... Go to PubMed...
  96. Sarlin T., Laitila A., Pekkarinen A., Haikara A. (2005): Effects of three Fusarium species on the quality of barley and malt. Journal of the American Society of Brewing Chemists, 63: 43-49. Go to original source...
  97. Sarlin T., Vilpola A., Kotaviita E., Olkku J., Haikara A. (2007): Fungal hydrophobins in the barley-to-beer chain. Journal of the Institute of Brewing, 113: 147-153. Go to original source...
  98. Savi G.D., Piacentini K.C., Bittencourt K.O., Scussel V.M. (2014): Ozone treatment efficiency on Fusarium graminearum and deoxynivalenol degradation and its effects on whole wheat grains (Triticum aestivum L.) quality and germination. Journal of Stored Product Research, 59: 245-253. Go to original source...
  99. Schapira S.F.D., Whithehead M.P., Flannigan B. (1989): Effects of the mycotoxin diacetoxyscripenol and deoxynivalenol on malting characteristics of barley. Journal of the Institute of Brewing, 95: 415-417. Go to original source...
  100. Schmidt M., Lynch K.M., Zannini E., Arendt E.K. (2018): Fundamental study on the improvement of the antifungal activity of Lactobacillus reuteri R29 through increased production of phenyllactic acid and reuterin. Food Control, 88: 139-148. Go to original source...
  101. Schwarz P.B., Beattie S., Casper H.H. (1996): Relationship between Fusarium infestation of barley and the gushing potential of malt. Journal of the Institute of Brewing, 102: 93-96. Go to original source...
  102. Schwarz P.B., Casper H.H., Beattie S. (1995): Fate and development of naturally occurring Fusarium mycotoxins during malting and brewing. Journal of the American Society of Brewing Chemists, 53: 121-127. Go to original source...
  103. Schwarz P.B., Horsley R.D., Steffenson B.J., Salas B., Barr J.M. (2006): Quality risks associated with the utilization of Fusarium head blight infected malting barley. Journal of the American Society of Brewing Chemists, 64: 1-7. Go to original source...
  104. Shephard G. (2011): Fusarium mycotoxins and human health. Plant Breeding Science, 64: 113-121. Go to original source...
  105. Shokribousjein Z., Deckers S.M., Gebrues K., Lorgouilloux Y., Baggerman G., Verachtert H., Delcour J.A., Etirnnr P., Rock J.M., Michiels C., Derdelincks G. (2011): Hydrophobins, beer foaming and gushing. Cerevisia, 35: 85-101. Go to original source...
  106. Shokribousjein Z., Philippaerts A., Riveros D., Titze J., Ford Y., Deckers S.M., Khalesi M., Delcour J.A., Gebruers K., Verachtert H., Ilberg V., Derdelinckx G., Sels B. (2014): A curative method for primary gushing of beer and carbonated beverages: Characterization and application of antifoam based hop oils. Journal of the American Society of Brewing Chemist, 72: 12-21. Go to original source...
  107. Sobrova P., Adam V., Vasatkova A., Beklova M., Zeman L., Kizek R. (2009): Deoxynivalenol and its toxicity. Interdisciplinary Toxicology, 3: 94-99. Go to original source... Go to PubMed...
  108. Song Y., Linderholm H.W., Wang C., Tian J., Huo Z., Gao P., Song Y., Guo A. (2019): The influence of excess precipitation on winter wheat under climate change in China from 1961 to 2017. Science of the Total Environment, 690: 189-196. Go to original source... Go to PubMed...
  109. Spanic V., Marcek T., Abicic I., Sarkanj B. (2017): Effect of Fusarium head blight on wheat grain and malt infected by Fusarium culmorum. Toxins, 10: 17. Go to original source... Go to PubMed...
  110. Spanic V., Zdunic Z., Drezner G., Sarkanj B. (2019): The pressure of Fusarium disease and its relation with mycotoxins in the wheat grain and malt. Toxins, 11: 198. Go to original source... Go to PubMed...
  111. Takenaka S. (2015): Studies on biological control mechanisms of Pythium oligandrum. Journal of General Plant Pathology, 81: 466-469. Go to original source...
  112. Tima H., Brückner A., Mohácsi-Farkas C., Kiskó G. (2016): Fusarium mycotoxins in cereals harvested from Hungarian fields. Food Additives & Contaminants: Part B, 9: 127-131. Go to original source... Go to PubMed...
  113. Timmusk S., Nevo E., Ayele F., Noe S., Niinemets Ü. (2020): Fighting Fusarium pathogens in the era of climate change: A conceptual approach. Pathogens, 9: 419. Go to original source... Go to PubMed...
  114. Tiwari B.K., Brennan C.S., Curran T., Gallagher E., Cullen P.J., O'Donnell C.P. (2010): Application of ozone in grain processing. Journal of Cereal Science, 51: 248-255. Go to original source...
  115. U.S. FDA (2010): Guidance for Industry and FDA: Advisory Levels for Deoxynivalenol (DON) in Finished Wheat Products for Human Consumption and Grains and Grain By-products Used for Animal Feed. U.S. Food and Drug Administration. Available at https://www.fda.gov/regulatory-information/search-fda-guidance-documents/guidance-industry-and-fda-advisory-levels-deoxynivalenol-don-finished-wheat-products-human (accessed Sept 8, 2020).
  116. Van Nierop S.N.E., Rautenbach M., Axcell B.C., Cantrell I.C. (2006): The impact of microorganisms on barley and malt quality - A review. Journal of the American Society of Brewing Chemists, 64: 69-78. Go to original source...
  117. Vaughan M., Backhouse D., Del Ponte E.M. (2016). Climate change impact on the ecology of Fusarium graminearum species complex and susceptibility of wheat to Fusarium head blight: A review. World Mycotoxin Journal, 9: 685-700. Go to original source...
  118. Vijayakumar M., Ilavenil S., Kim D.H., Arasu M.V., Priya K., Choi K.C. (2015): In-vitro assessment of the probiotic potential of Lactobacillus plantarum KCC-24 isolated from Italian rye-grass (Lolium multiflorum). Anaerobe, 32: 90-97. Go to original source... Go to PubMed...
  119. Wang H., Yan Y., Wang J., Zhang H., Qi W. (2012): Production and characterization of antifungal compounds produced by Lactobacillus plantarum IMAU10014. PLos ONE, 7: e29452. Go to original source... Go to PubMed...
  120. Wenda-Piesik A., Lemañczyk G., Twaru¼ek M., B³ajet-Kosicka A., Kazek M., Grajewski J. (2017): Fusarium head blight incidence and detection of Fusarium toxins in wheat in relation to agronomic factors. European Journal of Plant Pathology, 149: 515-531. Go to original source...
  121. Wolf-Hall C.E. (2007): Mould and mycotoxin problems encountered during malting and brewing. International Journal of Food Microbiology, 119: 89-94. Go to original source... Go to PubMed...
  122. Xue A., Chen Y., Seifert K., Guo W., Blackwell B., Harris L., Overy D. (2019): Prevalence of Fusarium species causing head blight of spring wheat, barley and oat in Ontario during 2001-2017. Canadian Journal of Plant Pathology, 41: 392-402. Go to original source...
  123. Yacoub A., Gerbore J., Magnin N., Chambon P., Dufour M.C., Corio-Costet M.F., Guyoneaud R., Rey P. (2016): Ability of Pythium oligandrum strains to protect Vitis vinifera L. by inducing plant resistance against Phaeomoniella chlamydospore, a pathogen involved in Esca, a grapevine trunk disease. Biological Control, 92: 7-16. Go to original source...
  124. Yépez A., Luz C., Meca G., Vignolo G., Mañes J., Aznar R. (2017): Biopreservation potential of lactic acid bacteria from Andean fermented food of vegetal origin. Food Control, 78: 393-400. Go to original source...
  125. Zachariasova M., Vaclavikova M., Lacina O., Vaclavik L., Hajslova J. (2012): Deoxynivalenol oligoglycosides: New 'masked' Fusarium toxins occurring in malt, beer, and breadstuff. Journal of Agriculture and Food Chemistry, 60: 9280-9291. Go to original source... Go to PubMed...

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