Czech J. Food Sci., 2017, 35(5):407-413 | DOI: 10.17221/172/2017-CJFS

Antidiabetic Compounds in Stem Juice from BananaFood Analysis, Food Quality and Nutrition

Dong Nguyen1, Alena Nováková2, Klára Spurná2, Jiří Hričko2, Huong Phung1, Jitka Viktorová3, Milena Stránská2, Jana Hajšlová2, Tomáš Ruml3*
1 Department of Biochemistry, Hanoi University of Pharmacy, Hanoi, Vietnam
2 Department of Food Analysis and Nutrition and 3Department of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Prague, Czech Republic

The stem juices from Musa × paradisiaca L. banana plants cultivated in their original natural habitat in Vietnam and those cultivated in a greenhouse in the Czech Republic were investigated for the presence of phytochemicals with antidiabetic potency. Respective bioactivities of these phytochemicals were also determined. Sample screening using ultrahigh performance liquid chromatography coupled with tandem high-resolution mass spectrometry (UHPL-HRMS/MS) method showed some differences in the pattern of bioactive compounds, both in terms of their number and concentration. p-Hydroxybenzoic and gallic acids were the predominant analytes found in stem juice from plants grown in Vietnam, while ferulic acid was the major compound found in juice obtained from greenhouse bananas. Despite differences in the occurrence of potentially antidiabetic compounds, both extracts exhibited comparable inhibitory activity against α-glucosidase and α-amylase.

Keywords: amylase; antidiabetic phytochemicals; plantan; Musa × paradisiaca; glucosidase inhibitor; inhibitor; extract cocktail

Published: October 31, 2017  Show citation

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Nguyen D, Nováková A, Spurná K, Hričko J, Phung H, Viktorová J, et al.. Antidiabetic Compounds in Stem Juice from Banana. Czech J. Food Sci. 2017;35(5):407-413. doi: 10.17221/172/2017-CJFS.
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    References

    1. Adisakwattana S., Moonsan P., Yibchok-Anun S. (2008): Insulin-releasing properties of a series of cinnamic acid derivatives in vitro and in vivo. Journal of Agricultural and Food Chemistry, 56: 7838-7844. Go to original source... Go to PubMed...
    2. Ashok Kumar B.S., Lakshman K., Nandeesh R., Arun Kumar P.A., Manoj B., Kumar V., Sheshadri Shekar D. (2011): In vitro alpha-amylase inhibition and in vivo antioxidant potential of Amaranthus spinosus in alloxan-induced oxidative stress in diabetic rats. Saudi Journal of Biological Sciences, 18: 1-5. Go to original source... Go to PubMed...
    3. Ayoola I.O., Gueye B., Sonibare M.A., Abberton M.T. (2017): Antioxidant activity and acetylcholinesterase inhibition of field and in vitro grown Musa L. species. Journal of Food Measurement and Characterization, 11: 488-499. Go to original source...
    4. Bajaj M., Hinge A., Limaye L.S., Gupta R.K., Surolia A., Kale V.P. (2011): Mannose-binding dietary lectins induce adipogenic differentiation of the marrow-derived mesenchymal cells via an active insulin-like signaling mechanism. Glycobiology, 21: 521-529. Go to original source... Go to PubMed...
    5. Borges C.V., de Oliveira Amorim V.B., Ramlov F., da Silva Ledo C.A., Donato M., Maraschin M., Amorim E.P. (2014): Characterisation of metabolic profile of banana genotypes, aiming at biofortified Musa spp. cultivars. Food Chemistry, 145: 496-504. Go to original source... Go to PubMed...
    6. Butterworth P.J., Warren F.J., Ellis P.R. (2011): Human alpha-amylase and starch digestion: an interesting marriage. Starch/Stärke, 63: 395-405. Go to original source...
    7. Coman C., Rugina O.D., Socaciu C. (2012): Plants and natural compounds with antidiabetic action. Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 40: 314-325. Go to original source...
    8. da Silva A.R., Cerdeira C.D., Brito A.R., Salles B.C.C., Ravazi G.F., Moraes G.D.I., Rufino L.R.A., de Oliveira R.B.S., Santos G.B. (2016): Green banana pasta diet prevents oxidative damage in liver and kidney and improves biochemical parameters in type 1 diabetic rats. Archives of Endocrinology Metabolism, 60: 355-366. Go to original source... Go to PubMed...
    9. Dineshkumar B., Mitra A., Manjunatha M. (2010): A comparative study of alpha amylase inhibitory activities of common anti-diabetic plants at Kharagpur 1 block. International Journal of Green Pharmacy, 4: 115-121. Go to original source...
    10. Famakin O., Fatoyinbo A., Ijarotimi O.S., Badejo A.A., Fagbemi T.N. (2016): Assessment of nutritional quality, glycaemic index, antidiabetic and sensory properties of plantain (Musa paradisiaca)-based functional dough meals. Journal of Food Science and Technology-Mysore, 53: 3865-3875. Go to original source... Go to PubMed...
    11. González-Montelongo R., Lobo M.G., González M. (2010): Antioxidant activity in banana peel extracts: testing extraction conditions and related bioactive compounds. Food Chemistry, 119: 1030-1039. Go to original source...
    12. Habtemariam S. (2011): A-glucosidase inhibitory activity of kaempferol-3-O-rutinoside. Natural Product Communications, 6: 201-203. Go to original source... Go to PubMed...
    13. Häkkinen M. (2013): Reappraisal of sectional taxonomy in Musa (Musaceae). Taxon, 62: 809-813. Go to original source...
    14. Jaber H., Baydoun E., El-Zein O., Kreydiyyeh S.I. (2013): Anti-hyperglycemic effect of the aqueous extract of banana infructescence stalks in Streptozotocin-induced diabetic rats. Plant Foods for Human Nutrition, 68: 83-89. Go to original source... Go to PubMed...
    15. Kandasamy S., Baggu C., Javagal M.R., Lingamallu J.R., Yenamandra V., Aradhya S.M. (2014): Antioxidant properties of isolated compounds from banana rhizome. Journal of Food Science, 79: H988-H1001. Go to original source... Go to PubMed...
    16. Kappel V.D., Cazarolli L.H., Pereira D.F., Postal B.G., Madoglio F.A., Buss Z.D.S., Reginatto F.H., Silva F.R. (2013): Beneficial effects of banana leaves (Musa × paradisiaca) on glucose homeostasis: multiple sites of action. Revista Brasileira de Farmacognosia, 23: 706-715. Go to original source...
    17. Kazeem M.I., Adamson J.O., Ogunwande I.A. (2013): Modes of inhibition of α-amylase and α-glucosidase by aqueous extract of Morinda lucida Benth leaf. BioMed Research International, Article ID 527570. doi: 10.1155/2013/527570 Go to original source... Go to PubMed...
    18. Mathew N.S., Negi P.S. (2017): Traditional uses, phytochemistry and pharmacology of wild banana (Musa acuminata Colla): a review. Journal of Ethnopharmacology, 196: 124-140. Go to original source... Go to PubMed...
    19. Oboh G., Ademosun A.O., Ayeni P.O., Omojokun O.S., Bello F. (2014): Comparative effect of quercetin and rutin on α-amylase, α-glucosidase, and some pro-oxidant-induced lipid peroxidation in rat pancreas. Comparative Clinical Pathology, 24: 1103-1110. Go to original source...
    20. Oboh G., Agunloye O.M., Adefegha S.A., Akinyemi A.J., Ademiluyi A.O. (2015): Caffeic and chlorogenic acids inhibit key enzymes linked to type 2 diabetes (in vitro): a comparative study. Journal of Basic and Clinical Physiology and Pharmacology, 26: 165-170. Go to original source... Go to PubMed...
    21. Oboh G., Ogunsuyi O.B., Ogunbadejo M.D., Adefegha S.A. (2016): Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose. Journal of Food and Drug Analysis, 24: 627-634. Go to original source... Go to PubMed...
    22. Oliveira L., Freire C., Silvestre A., Cordeiro N., Torres I., Evtuguin D. (2005): Steryl glucosides from banana plant Musa acuminata Colla var cavendish. Industrial Crops and Products, 22: 187-192. Go to original source...
    23. Oliveira L., Freire C., Silvestre A., Cordeiro N., Torres I., Evtuguin D. (2006): Lipophilic extractives from different morphological parts of banana plant "Dwarf Cavendish". Industrial Crops and Products, 23: 201-211. Go to original source...
    24. Padam B.S., Tin H.S., Chye F.Y., Abdullah M.I. (2014): Banana by-products: an under-utilized renewable food biomass with great potential. Journal of Food Science and Technology, 51: 3527-3545. Go to original source... Go to PubMed...
    25. Porter W.H., Jennings C.D., Wilson H.D. (1986): Measurement of α-glucosidase activity in serum from patients with cystic fibrosis or pancreatitis. Clinical Chemistry, 32: 652-656. Go to original source...
    26. Ramu R., Shirahatti P.S., Zameer F., Ranganatha L.V., Prasad M.N. (2014): Inhibitory effect of banana (Musa sp. var. Nanjangud rasa bale) flower extract and its constituents Umbelliferone and Lupeol on α-glucosidase, aldose reductase and glycation at multiple stages. South African Journal of Botany, 95: 54-63. Go to original source...
    27. Rebello L.P.G., Ramos A.M., Pertuzatti P.B., Barcia M.T., Castillo-Muñoz N., Hermosín-Gutiérrez I. (2014): Flour of banana (Musa AAA) peel as a source of antioxidant phenolic compounds. Food Research International, 55: 397-403. Go to original source...
    28. Rubert J., Lacina O., Zachariasova M., Hajslova J. (2016): Saffron authentication based on liquid chromatography high resolution tandem mass spectrometry and multivariate data analysis. Food Chemistry, 204: 201-209. Go to original source... Go to PubMed...
    29. Saltan F.Z., Okutucu B., Canbay H.S., Ozel D. (2017): In vitro α-glucosidase and α-amylase enzyme inhibitory effects in Elaeagnus angustifolia leaves extracts. Eurasian Journal of Analytical Chemistry, 12:117-126. Go to original source...
    30. Saltan F.Z., Okutucu B., Canbay H.S., Ozel D. (2017): In vitro α-glucosidase and α-amylase enzyme inhibitory effects in Elaeagnus angustifolia leaves extracts. Eurasian Journal of Analytical Chemistry, 12: 117-126. Go to original source...
    31. Satyavati G., Neeraj T., Madhu S. (1989): Indigenous plant drugs for diabetes mellitus. International Journal Diabetes in Developing Countries, 9: 1-35.
    32. Skop V., Cahova M., Dankova H., Papackova Z., Palenickova E., Svoboda P., Zidkova J., Kazdova L. (2014): Autophagy inhibition in early but not in later stages prevents 3T3-L1 differentiation: effect on mitochondrial remodeling. Differentiation, 87: 220-229. Go to original source... Go to PubMed...
    33. Telagari M., Hullatti K. (2015): In-vitro α-amylase and α-glucosidase inhibitory activity of Adiantum caudatum Linn. and Celosia argentea Linn. extracts and fractions. Indian Journal of Pharmacology, 47: 425-429. Go to original source... Go to PubMed...

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