Czech J. Food Sci., 2011, 29(10):S36-S41 | DOI: 10.17221/303/2011-CJFS

Contribution to the immunomodulatory characteristics of probiotic bacteria

Alexandra Šalaková1, Jiřina Bártová2, Jan Drbohlav1, Petr Roubal1
1 Dairy Research Institute Ltd., Prague, Czech Republic
2 Institute of Dental Research, Prague, Czech Republic

We monitored the impact of selected probiotic strains on the human immune system. 13 strains of lactic acid bacteria (Lactobacillus acidophilus, Lactobacillus helveticus, Enterococcus faecium, Streptococcus thermophilus, and Propionibacterium freudenreichii subsp. shermanii), used in the production of functional foods, were tested from the point of view of their ability to stimulate a range of cytokines. The selected cytokines have regulatory properties; they affect the progression of inflammation and the inhibition of inflammatory response, and they play a role in humoral immunity, allergies, and cell-mediated immunity. The tested strains showed a specific interaction with the immune system. It was found that the P. freudenreichii strain showed significant levels of IFN gamma cytokine.

Keywords: Lactobacillus acidophilus; Lactobacillus helveticus; Enterococcus faecium; Streptococcus thermophilus; Propionibacterium freudenreichii subsp. shermanii; immunomodulation

Published: December 31, 2011  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Šalaková A, Bártová J, Drbohlav J, Roubal P. Contribution to the immunomodulatory characteristics of probiotic bacteria. Czech J. Food Sci. 2011;29(Special Issue):S36-41. doi: 10.17221/303/2011-CJFS.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Aureli P., Capurso L., Castellazzi A., Clerici M., Giovannini M., Morelli L., Poli A., Pregliasco F., Salvini F., Zuccotti G. (2011): Probiotics nad health: an evidencebased review. Pharmacological Research, 63: 366-376. Go to original source... Go to PubMed...
    2. Drbohlav J. (2005): Mléko-významná součást zdravé a bezpečné výživy. [Výzkumná zpráva.] VÚM s.r.o., Praha.
    3. Fabian E., Elmadfa I. (2006): Influence of daily consumption of probiotic nad convential yoghurt on plasma lipid profile in young healthy women. Annals of Nutrition and Metabolism, 50: 387-393. Go to original source... Go to PubMed...
    4. Gueimonde M., Sakata S., Kalliomaki M., Isolauri E., Benno Y., Salminen S. (2006): Effect of maternal consumption of lactobacillus GG on transfer and establishment of fecal bifidobacterial microbiota in neonates. Journal of Pediatric Gastroenterology and Nutrition, 42: 166-170. Go to original source... Go to PubMed...
    5. Hoesl C., Altwein J. (2005): The probiotic approach: an alternative treatment option in urology. European Urology, 47: 288-296. Go to original source... Go to PubMed...
    6. Kokešová A, Frolová L, Kverka M, Sokol D, Rossmann P, Bártová J, Tlaskalová-Hogenová H. (2006): Oral administration of probiotic bacteria (E. coli Nissle, E. coli O83, Lactobacillus casei) influences the severity of dextran sodium sulfate-induced colitis in BALB/c mice. Folia Microbiologica, 51: 478-484. Go to original source... Go to PubMed...
    7. Lammers K.M., Brigidi P., Vitali B., Gionchetti P., Rizzello F., Caramelli E., Matteuzzi D., Campieri M. (2003): Immunomodulatory effects of probiotic bacteria DNA: IL-1 and IL-10 response in human peripheral blood mononuclear cells. FEMS Immunology and Medical Microbiology, 38: 165-172. Go to original source... Go to PubMed...
    8. Lodinová-Žádníková R. (2002): Probiotika v pediatrii. Snížení rizika nosokomiálních infekcí perorálním osídlením probiotickým kmenem E. coli po narození a jeho vliv na frekvenci opakovaných infekcí a alergií po 10 a 20 letech. Alergie, č. 4: 275-280.
    9. Meurman J.H., Sanz M., Janket S.J. (2004): Oral health, atherosclerosis and cardiovascular disease. Critical Reviews in Oral Biology and Medicine, 15: 403-413. Go to original source... Go to PubMed...
    10. Mosmann T.R., Coffman R.L. (1989): TH1 and TH2 cells: Different patterns of lymphokine secretion lead different functional properties. Annual Review of Immunology, 7: 145-173. Go to original source... Go to PubMed...
    11. Prakash S., Rodes L., Coussa-Charlez M., Tomaro_ Duchesneau C. (2011): Gut microbiota: next frontier in understanding human health and development of biotherapeutics. Biologics: Targets and Therapy, 5: 71-86. Go to original source... Go to PubMed...
    12. Schultz M. (2008): Clinical use of E. coli Nissle 1917 in inflammatory bowel disease. Inflammatory Bowel Diseases, 14: 1012-1018. Go to original source... Go to PubMed...
    13. Smith A., Buchinsky F., Post J. (2011): Eradicating chronic ear, nose, and throat infection: a systematically conducted literature review of advances in biofilm treatment. Otolaryngology - Head Neck Surgery, 144: 338-347. Go to original source... Go to PubMed...
    14. Torii A., Torii S., Fujiwara S., Tanaka H., Inagaki N., Nagai H. (2007): Lactobacillus acidophilus strain L-92 regulates the production of Th1 cytokine as well as Th2 cytokines. Allergology International, 56: 293-301. Go to original source... Go to PubMed...
    15. Verna E., Lucak S. (2010): Use of probiotics in gastrointestinal disorders: what to recommend? Therapeutic Advances in Gastroenterology, 3: 307-319. Go to original source... Go to PubMed...

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY NC 4.0), which permits non-comercial use, distribution, and reproduction in any medium, provided the original publication is properly cited. No use, distribution or reproduction is permitted which does not comply with these terms.


    Return to the content