Czech J. Food Sci., 2011, 29(6):641-646 | DOI: 10.17221/22/2011-CJFS

Fluoroquinolone residues in raw cow's milk

Pavlína Navrátilová, Ivana Borkovcová, Jana Vyhnálková, Lenka Vorlová
Department of Milk Hygiene and Technology, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic

The aim of the study was to monitore the levels of fluoroquinolone residues in bulk samples of raw cow's milk. The bulk samples of raw cow's milk (n = 150) were obtained from 58 different milk suppliers in the South Moravian and Vysočina Regions. The samples were analysed by reverse phase high-performance liquid chromatography method with fluorescence detection and gradient elution. 87.3% of the raw milk samples were positive for the fluoroquinolones residues. Flumequine was present in none of the samples. The levels of other fluoroquinolones investigated were below the recommended maximum residue limit. The results of the study indicate that fluoroquinolones are frequently administered to the dairy cows in spite of the recommendations of CVMP. The most frequently determined was enrofloxacin and its indicator residue, i.e. ciprofloxacin. An efficient control of the veterinary drugs residues in milk is very important to ensure the safety of the milk and milk products.

Keywords: veterinaty drug; RP HPCL; food safety; MRL; LOD; LOQ

Published: December 31, 2011  Show citation

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Navrátilová P, Borkovcová I, Vyhnálková J, Vorlová L. Fluoroquinolone residues in raw cow's milk. Czech J. Food Sci. 2011;29(6):641-646. doi: 10.17221/22/2011-CJFS.
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