Czech J. Food Sci., 2007, 25(1):32-38 | DOI: 10.17221/739-CJFS

Sodium cholate sorption on N-octadecylpectinamide in comparison with cholestyramine

Andriy Synytsya, Lucie Fesslová, Milan Marounek, Jana Čopíková
Department of Carbohydrate Chemistry and Technology, Faculty of Food and Biochemical Technology, Institute of Chemical Technology Prague, Prague, Czech Republic

N-Octadecylpectinamide is hydrophobically modified HM citrus pectin. Previously, it had been prepared by heterogeneous amino-de-alkoxylation of initial pectin with n-octadecylamine in dimethylsulphoxide and characterised as potential hydrophobic sorbent and cholesterol lowering agent. The sorption properties of N-octadecylpectinamide were analysed in comparison with cholestyramine, an effective bile acid sequestrant. Sorption experiments were carried out using sodium cholate as a model bile acid. Cholate concentration was estimated by enzymatic spectroscopic method. Sorption kinetics curves and sorption isotherms of both sorbents were constructed and analysed.

Keywords: N-octadecylpctinamide; cholestyramine; sodium cholate; sorption kinetics; sorption isotherm

Published: February 28, 2007  Show citation

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Synytsya A, Fesslová L, Marounek M, Čopíková J. Sodium cholate sorption on N-octadecylpectinamide in comparison with cholestyramine. Czech J. Food Sci. 2007;25(1):32-38. doi: 10.17221/739-CJFS.
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