Czech J. Food Sci., 2004, 22(3):87-94 | DOI: 10.17221/3411-CJFS

Modern method of lactic acid recovery from fermentation broth

V. Hábová, K. Melzoch, M. Rychtera
Department of Fermentation Chemistry and Bioengineering, Institute of Chemical Technology in Prague, Prague, Czech Republic

Electrodialysis was used for lactic acid recovery from fermentation broth. In the first step, lactate was recovered and concentrated by desalting electrodialysis, and the second step was electroconversion of lactate to lactic acid by water-splitting electrodialysis. The final lactic acid concentration of 151 g/l was obtained. Total energy required in both electrodialysis processes was about 1.5 kWh per 1 kg of lactic acid obtained. The fermentation broth had to be pretreated prior to the electrodialysis experiments. The pretreatment consisted of ultrafiltration, decolourisation, and the removal of multivalent metal ions.

Keywords: lactic acid recovery; electrodialysis; pretreatment of fermentation broth

Published: June 30, 2004  Show citation

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Hábová V, Melzoch K, Rychtera M. Modern method of lactic acid recovery from fermentation broth. Czech J. Food Sci. 2004;22(3):87-94. doi: 10.17221/3411-CJFS.
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    References

    1. B D.-M., J M.-Z., Z X.-M., B R., S F., L X.-G., X S.-M. (2003a): (+)-lactic acid production by pellet-form Rhizopus oryzae R1021 in a stirred tank fermentor. Chem. Eng. Sci., 58: 785-791. Go to original source...
    2. B D.-M., W Q., Y Z.-H., Z X.-M., L X.-G., X S.-M. (2003b): Fed-batch fermentation of Lactobacillus lactis for hyper-production of -lactic acid. Biotechnol. Le., 25: 1833-1835.
    3. B M. (2002): Production of organic acids by bipolar electrodialysis: realizations and perspectives. Desalination, 144: 157-162. Go to original source...
    4. B P., K W., T W., B H. (1998): Integrated bioprocess for the simultaneous production of lactic acid and dairy sewage treatment. Bioprocess Eng., 19: 321-329. Go to original source...
    5. C X., Y H.S., K Y.-M. (2002): Recovery of -(+)-lactic acid by anion exchange resin Amberlite IRA-400. Biochem. Eng. J., 11: 189-196. Go to original source...
    6. D R., T S.P., B P.V., M S.-H., F J.R. (1995): Technological and economic potential of poly-lactic acid and lactic acid derivates. FEMS Microbiol. Rev., 16: 221-231. Go to original source...
    7. C M., I K., K K. (1987): Continuous glucose fermentation for lactic acid production: Recovery of acid by electrodialysis. Chem-IngTech., 59: 952-954. Go to original source...
    8. C J.-H., K S.-H., M S.-H. (2002): Recovery of lactic acid from sodium lactate by ion substitution using ion-exchange membrane. Sep. Purif. Technol., 28: 69-79. Go to original source...
    9. F P., S K. (1999): Recovery of lactic acid from aqueous model solutions and fermentation broths. Process Biochem., 34: 685-696. Go to original source...
    10. H V., M K., R M., P L., M V. (2001): Application of electrodialysis for lactic acid recovery. Czech J. Food Sci., 19: 73-80. Go to original source...
    11. H V., M K., R M. (2004): Electrodialysis as a useful technique for lactic acid separation from a model solution and a fermentation broth. Desalination, 163: 361-372. Go to original source...
    12. H V., Š J., Š E., I J. (1993): Isolation of free lactic acid using electrodialysis. Biotech. Tech., 7: 63-68. Go to original source...
    13. H J.H. (2004): Biotechnologies: past history, present state and future prospects. Trends Food Sci. Technol., 15: 3-18. Go to original source...
    14. I P.V., L Y.Y. (1999): Product inhibition in simultaneous saccharification and fermentation of cellulose into lactic acid. Biotechnol. Le., 21: 371-373.
    15. J R., M J L., B P. (1996): Semicontinuous production of lactic acid in a bioreactor coupled with nanofiltration membranes. Enzyme Microb. Technol., 19: 614-619. Go to original source...
    16. J B., H P.L., L P. (2003): Rhizopus arrhizus - a producer for simultaneous saccharification and fermentation of starch waste materials to (+)-lactic acid. Biotechnol. Le., 25: 1983-1987. Go to original source... Go to PubMed...
    17. K J.S., K J., R M. (1996): Lactic acid. In: R M. (ed.): Biotechnology. Vol. 6 - Products of Primary Metabolism. VCH, Weinheim: 294-306.
    18. K Y.H., M S.-H. (2001): Lactic acid recovery from fermentation broth using one-stage electrodialysis. J. Chem. Technol. Biotechnol., 76: 169-178. Go to original source...
    19. L E.G., M S.-H., C Y.K., Y I.-K., C H.N. (1998): Lactic acid recovery using two-stage electrodialysis and its modelling. J. Membr. Sci., 145: 53-66. Go to original source...
    20. L H., M R., K C. J., S W., S G., D I., J S.A. (2004): An electrokinetic bioreactor: using direct electric current for enhanced lactic acid fermentation and product recovery. Tetrahedron, 60: 655-661. Go to original source...
    21. M M., T T., K K. (1998): Separation of lactic acid using polymeric membrane containing a mobile carrier. J. Ferment. Bioeng., 85: 483-487. Go to original source...
    22. M -T G., H M., K M., T H., H T. (2003): Production of -lactic acid by electrodialysis fermentation (EDF). Process Biochem. (21 November 2003, www.sciencedirect.com).
    23. S A., S M. (2002): Properties of lactic acid based polymers and their correlation with composition. Prog. Polym. Sci., 27: 1123-1163. Go to original source...
    24. T J.M.K., K J., R T. (1994): Lactic acid separation from fermentation broths by reverse osmosis and nanofiltration. J. Membr. Sci., 92: 185-197. Go to original source...
    25. T S.P., D R., H M., H Y., F J.R. (1999): Production of organic acids by electrodialysis/ pervaporation process. Membrane Technol., 1999, No. 109: 8-12. Go to original source...
    26. V R T.B. (1985): Lactic acid. In: Y M.M. (ed.): Comprehensive Biotechnology. Pergamon Press, New York: 761-775.
    27. W K.L., P V.G., H A.B.M., V G.F. (2003): Intensification of enzymatic conversion of glucose to lactic acid by reactive extraction. Chem. Eng. Sci., 58: 3385-3393. Go to original source...

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