RT Journal Article
SR Electronic
A1 Riaz, Muhammad
A1 Fatima, Humaira
A1 Misbah ur Rehman, Muhammad
A1 Qadir, Rahman
A1 Hussain, Shabbir
A1 Hafeez, Abdul
A1 Siddique, Abu Bakar
T1 Appraisal of antioxidant potential and biological studies of bogan bail (Bougainvillea glabra) leaf extracts using different solvents
JF Czech Journal of Food Sciences
YR 2021
VO 39
IS 3
SP 176
OP 180
DO 10.17221/273/2020-CJFS
UL https://cjfs.agriculturejournals.cz/artkey/cjf-202103-0004.php
AB Current research work was performed to evaluate the antioxidant, antidiabetic, thrombolytic, and cytotoxic potential of Bougainvillea glabra leaf extracts with different solvents. Extraction of leaves was carried out by maceration using solvents of various polarity such as n-hexane, chloroform, ethyl acetate, n-butanol, and methanol. The highest values of total phenolic and flavonoid contents were assessed in methanolic extract, such as 58.57% and 29.41%, respectively. Antioxidant potential was measured by DPPH free radical, showing 65.16% scavenging activity in methanolic extract. Similarly, the reducing power of methanolic extract was also measured. Hemolytic activity of B. glabra leaf extracts was evaluated, and maximum percentage lysis was found as 6.86% in chloroform extract. The thrombolytic activity of B. glabra leaf extracts was evaluated against human red blood cells, and the maximum percentage of clot lysis was 59.10% in chloroform extract. Maximum antidiabetic activity (16.20%) was observed in methanolic extract. Overall, the presented results reveal that bogan bail extract is capable of being employed in nutra-pharmaceutical industry.